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Six months after the second jab… July 23, 2021

Posted by WorldbyStorm in Uncategorized.
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...it appears that vaccines may begin to lose effectiveness.

In a statement, the company said it will seek authorization in August and will release more data first, CNN reported. 

“As seen in real world data released from the Israel Ministry of Health, vaccine efficacy in preventing both infection and symptomatic disease has declined six months post-vaccination, although efficacy in preventing serious illnesses remains high,” the statement said, according to multiple news outlets. 

Though it’s not disastrous… 

Israeli officials are reporting a 30% decrease in the effectiveness of the Pfizer COVID-19 vaccine to prevent infection and mild to moderate cases. At the same time, however, protection against hospitalization and severe illness remains robust.

An excellent point too in the article linked above.

People may have unrealistic expectations regarding breakthrough infections, Anna Durbin, MD, said. “It seems that people are almost expecting ‘sterilizing immunity’ from these vaccines,” she said, explaining that would mean complete protection from infection.

Expectations may be high “because these vaccines have been so effective,” added Durbin, who is also affiliated with the Johns Hopkins Center for Global Health.

Anecdata suggests, from conversations, that this idea of sterilising immunity is indeed one with some currency. Indeed so much of what we hear from industry lobbying groups seems predicted on the idea that vaccines are completely effective. But it spreads much wider in our societies than that. And it’s difficult not to blame government’s for this. They too have given the impression that vaccinations are the single route back to ‘normality’, rather than underlining that the path is going to be more circuitous and require a suite of approaches, mask wearing, some degree of social distancing in certain contexts and so on. It’s not that governments ignore that completely, rather that they tend to focus overly on the vaccines and insufficiently on all else. 

But the point about a six month period of robust effectivity, followed by a decline in that, is of huge importance. It suggests that booster shots will be necessary and that ‘living with’ the virus is going to entail precisely that suite of approaches mentioned above. Does it then become a little like a more virulent and debilitating flu?

Comments»

1. sonofstan - July 23, 2021

I was told when I got my second shot that they intended calling over 60s in for a booster from September onwards. This was with AZ here in England

Liked by 1 person

sonofstan - July 23, 2021

I remember thinking ‘that’ll be nice for them’ and then realising they meant me..

Liked by 3 people

2. Jim Monaghan - July 23, 2021

I think like the flu jab, annual, with a major change every few years to take care of major changes in the virus. I wonder if over a few hundred years that Darwin’s law will apply to anti-vaxxers.

Liked by 2 people

Arthur Owen - July 23, 2021

No stupidity will turn out to be perennial.

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3. Liberius - July 23, 2021

However, World Health Organization officials insisted there was not enough evidence to show that third doses are needed, and said Pfizer should concentrate instead on improving vaccine access around the world…

…Dr Soumya Swaminathan, the chief WHO scientist, said: “At this point … there is no scientific evidence to suggest that boosters are definitely needed.”

Swaminathan said the WHO would make recommendations on booster shots “based on the science and data, not on individual companies declaring that the vaccines should now be administered as a booster dose”.

Dr Michael Ryan, the WHO emergencies chief, suggested that if rich countries decide to administer booster shots rather than to donate them to the developing world, “we will look back in anger and I think we will look back in shame.”

The WHO thinks a little differently, it’s worth keeping the above in mind, it might well become necessary but it’s not obvious yet.

On a semi-related note, first dose today, the Show Centre is a wholely inappropriate location for a vaccination centre, very unfriendly for pedestrians like me.

https://www.theguardian.com/world/2021/jul/12/coronavirus-pfizer-booster-vaccine-who-disparities

Liked by 1 person

4. Bagatelle's Unbearded Tartars - July 24, 2021

I would like an immunologist to weigh in here as an authoritative source but (and this comes with double extra health warnings that I’m an internet gobshite) the report is that levels of antibodies against COVID fall off after 6 months. The memory B-cells are still there ready and waiting to pump out new antibodies. And this is how all vaccines work and have always worked. Could this be a journalist reading the reports on antibody level decrease and sprinting to erroneous conclusion on efficacy?

Liked by 1 person

WorldbyStorm - July 24, 2021

Yes, that’s a fair point. My reading of it is that there’s a bit of confidence that there will be a continuing response, though perhaps not at quite the same level. But yes, definitely it doesn’t seem to be a cliff like drop.

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